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Sumatriptan is a medication that is used to treat migraines and cluster headaches. It should be taken at the onset of pain, but does not prevent the migraine or cluster headache from occurring in the first place.


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  • It usually works within 30 to 60 minutes
  • It is part of the triptan family of medications
  • It does not work on tension headaches
  • It is important to read the patient leaflet for a full list of side effects and cautions.

Sumatriptan is a serotonin (5-HT1) agonist. It works on the receptors at blood vessels and nerve endings within the brain.

  1. Blood vessel dilation (widening) is responsible for some of the pain of a migraine or cluster headache. Sumatriptan causes constriction (narrowing) of the vessels within the head to reduce the pain of a migraine or cluster headache.
  2. Sumatriptan prevents the release of neuropeptides that would cause vessels to dilate. This also reduces the pain associated with blood vessel dilation. sumatriptan over the counter
  3. The medication reduces the transmission of pain signals along the nerves within the brain, reducing your perception of the pain of the migraine or cluster headache.

Sumatriptan is available in a range of forms. Each should be taken as soon as you feel the migraine or cluster headache starting.

Tablets should be swallowed with water. Tablets usually work within 30 to 60 minutes.

Breathe deeply to inhale the dose. The nasal spray usually works within 15 minutes. Buy sumatriptan UK, sumatriptan over the counter

Migraine injections come in pre-filled syringes. The injection can work within 10 to 15 minutes. buy sumatriptan tablets

The usual dose when taking tablets is 50mg at the onset of a migraine or cluster headache.

The nasal spray is available in preparations of 10mg or 20mg, and your prescriber will decide which strength will suit you best.

An injection of sumatriptan usually contains 6mg. Buy sumatriptan nasal spray

Many people will have no side effects when taking sumatriptan. They include:

  • Nausea and vomiting (feeling sick or being sick)
  • Feeling dizzy or tired
  • Feeling hot or cold
  • Nasal irritation, an unpleasant taste in your mouth, or nosebleeds with the nasal spray
  • Bruising or swelling at the injection site when using the injection.

Occasionally, more serious side effects can occur including:

  • Heaviness, tingling or tightness in the face, arms, legs or chest
  • Feelings of warmth or cold in the face, arms, legs or chest.

If you have a severe allergic reaction (anaphylaxis) including breathlessness, or lip or tongue swelling, call 999 immediately.

Sumatriptan is not suitable for everyone, including some people who:

  • Take certain antidepressants
  • Have heart or circulation problems including high blood pressure
  • Have had a stroke or mini-stroke
  • Have seizures
  • Have liver disease
  • Are pregnant or breastfeeding
  • Are heavy smokers.

Even if one or more of these affects you, sumatriptan could still be a suitable treatment option.

A prescriber from EU Meds will review your current medications, including any herbal remedies or supplements, to ensure that sumatriptan will not interact with them. Once prescribed, you can order sumatriptan online for home delivery.

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